Thank you for your comments, Geoffrey. But aren't biological systems physical systems? The 'connecting paradigm' is universal consciousness, one that is fundamental, primary and causal, from which all arises. The question of how awareness can be generated at the macro level by sub-atomic particles/waves at the micro level is the 'hard problem' of consciousness which can be set aside if one accepts that consciousness is the ground of being. I have many articles on this and related subjects at Medium. Best wishes, Geoff